CAS number | 914675-52-8 |
Molecular formula | C18H21BO2 |
Product name | Biphenyl-2-boronic acid pinaco |
Molecular Structure | ![]() |
Molecular Weight:280.16900
PSA:18.46000
LogP:3.65280
Biphenyl-2-boronic acid pinacol ester (BPBAPE) is a novel organoboron compound with important applications in organic synthesis, including synthesis of novel pharmaceuticals, agrochemicals, and materials. It is a versatile reagent for condensation, cyclization, and other complex transformations. BPBAPE has several advantages over traditional boronic acids, including enhanced reactivity, enhanced solubility, and greater thermal stability.
BPBAPE is a versatile reagent for a variety of organic transformations, including condensation, cyclization, and other complex transformations. It is a highly reactive and thermally stable organoboron compound, which can be employed in a variety of organic transformations under mild conditions. The reagent is especially useful in the synthesis of heterocycles and carbocycles. BPBAPE is also used in the synthesis of novel pharmaceuticals, agrochemicals, and materials.
BPBAPE is a white to off-white, odorless powder that is soluble in organic solvents. It is stable to air, light, and moisture and has a relatively high melting point. The compound is synthesized by reacting 2-bromobiphenyl with pinacol boronic acid. The reaction is carried out in an inert solvent, such as dichloromethane, and is typically complete in a few minutes. The product is purified by recrystallization from an appropriate solvent, such as ethyl acetate or toluene.
BPBAPE is a highly reactive and thermally stable organoboron compound, which can be employed in a variety of organic transformations under mild conditions. The reagent is especially useful in the synthesis of heterocycles and carbocycles. Its enhanced reactivity makes it a valuable tool in the synthesis of various compounds. BPBAPE has been used in the synthesis of a number of compounds, including but not limited to carbohydrates, steroids, peptides, and nucleotides.
BPBAPE is an important reagent in the synthesis of novel pharmaceuticals, agrochemicals, and materials. Its enhanced reactivity and improved solubility make it a valuable tool for the synthesis of a wide range of compounds. Its enhanced thermal stability makes it useful for synthesizing compounds that require high temperatures for their formation. BPBAPE is a versatile reagent for a variety of organic transformations, including condensation, cyclization, and other complex transformations.