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Pharmaceutical intermediates

Guanidine thiocyanate

CAS number

593-84-0

Molecular formula CH5N3.CHNS
Product name Guanidine thiocyanate
Molecular Structure

Appearance: white crystal powder
Purity: 99.5% min
Density 1.103 g/mL at 20ºC
Boiling Point 132.9ºC at 760 mmHg
Melting Point 118-122ºC
Flash Point 34.2ºC
Refractive Index n20/D 1.482
Stability Stability Stable, but light sensitive. Incompatible with acids (contact releases very toxic gas), strong oxidising agents.
Storage Condition Store at RT.


Guanidine thiocyanate is an essential reagent used in molecular biology, biochemistry, and molecular biology research. It is an organic compound with a molecular formula of C3H7N3O2S. Guanidine thiocyanate is a white hygroscopic powder that is highly soluble in water, ethanol, and methanol. It is used for the denaturation of proteins and nucleic acids, and for the extraction and purification of nucleic acids. It can also be used for the preparation of buffers, for the determination of cations, and for the extraction of proteins. Guanidine thiocyanate is stable when stored at room temperature and is non-toxic.


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