1175203-78-7

Molecular Weight：445.34900

PSA：0.00000

LogP：7.94580

5-bromo-spiro[fluorene-7,9'-benzofluorene] is a member of the benzofluorene family of compounds with a unique spirocyclic ring system. It is a colorless crystalline solid, soluble in organic solvents and slightly soluble in water. 

5-bromo-spiro[fluorene-7,9'-benzofluorene] was first synthesized in the late 1950s by the research team of Prof. Robert B. Woodward at Harvard University. Since then, it has been studied extensively as a model compound for the study of chemical reactivity and synthetic methods. It is a versatile building block for the synthesis of complex molecules, and its ring system can be altered by substituent groups to give rise to new compounds with interesting physical and chemical properties.

5-bromo-spiro[fluorene-7,9'-benzofluorene] can be used as a starting material for the synthesis of a wide range of heterocyclic compounds, including spirooxindoles, spirothiadiazoles, spiroimidazolidines, and spirofurans. It is also used as an intermediate in the synthesis of dyes and pigments, pharmaceuticals, and agrochemicals. In addition, 5-bromo-spiro[fluorene-7,9'-benzofluorene] has been used as a ligand in transition metal-catalyzed reactions such as the Heck reaction and Suzuki-Miyaura coupling. 

5-bromo-spiro[fluorene-7,9'-benzofluorene] is available in the form of white crystalline powder. It is highly stable and can be stored at room temperature away from light and moisture. It should be handled with caution due to its potential to form combustible dust-air mixtures and to cause skin and eye irritation.

In conclusion, 5-bromo-spiro[fluorene-7,9'-benzofluorene] is a valuable chemical compound with a broad range of applications in the fields of organic synthesis, pharmaceuticals, agrochemicals, and dyes and pigments. Its unique spirocyclic ring system makes it a versatile building block for the synthesis of complex molecules, and its reactivity can be altered by adding substituent groups. It is widely used as an intermediate in the synthesis of a wide range of heterocyclic compounds and as a ligand in transition metal-catalyzed reactions.