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Electronical chemicals

9,9'-spirobifluorene-4-yl pinacol boronic ester

CAS number

1161009-89-7

Molecular formula C31H27BO2
Product name 9,9'-spirobifluorene-4-yl pinacol boronic ester
Molecular Structure

Molecular Weight:442.35600

PSA:18.46000

LogP:6.32930


9,9'-spirobifluorene-4-yl pinacol boronic ester (SBFPE) is a useful intermediate in organic synthesis. It is a symmetric boronic ester which has a spirobifluorene core. SBFPE has been used in various pharmaceutical and agrochemical research applications.


SBFPE has a molecular formula of C17H19BO2 and a molecular weight of 282.18 g/mol. It is a white to light brown solid with a melting point of 91-93 ºC. It is soluble in common organic solvents such as dichloromethane, chloroform, toluene and tetrahydrofuran.


SBFPE can be prepared by the reaction of the corresponding boronic acid and the appropriate pinacol ester at room temperature in dichloromethane or tetrahydrofuran. The reaction does not require the use of a catalyst and typically yields products with a high degree of purity.


SBFPE has been used in a variety of applications, including in the synthesis of spirocyclic compounds such as spiroketals, spiroketene derivatives, and spirocyclic ketals. It has also been used in the synthesis of functionalized polymers and in the synthesis of spirobiindanones.


In addition, SBFPE has been used in the synthesis of various heterocyclic compounds and in the synthesis of α-amino acids. It has also been used in the synthesis of various pyrrole derivatives and in the synthesis of various enantiomerically pure compounds.


SBFPE is a valuable intermediate for organic synthesis and has a wide range of potential applications. It is a versatile reagent which can be used in the synthesis of a variety of compounds, such as spirocyclic compounds, functionalized polymers, spirobiindanones, heterocycles, pyrroles, and enantiomerically pure compounds. In addition, it is available from a variety of commercial sources and is typically supplied in convenient packaging sizes.


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