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Electronical chemicals

4-(Naphthalene-2-yl)phenylboronic acid pinacol ester

CAS number

1092390-02-7

Molecular formula C22H23BO2
Product name 4-(Naphthalene-2-yl)phenylboronic acid pinacol ester
Molecular Structure

Molecular Weight:330.22800

PSA:18.46000

LogP:4.80600

4-(Naphthalene-2-yl)phenylboronic acid pinacol ester (4-NPPBE) is a boronic acid derivative of naphthalene and phenylboronic acid. It is a white to off-white powder with a molecular weight of 364.39 g/mol. This compound is widely used in organic synthesis as a building block for the synthesis of a wide range of organic molecules, such as pharmaceuticals, agrochemicals, and materials.


4-NPPBE is a useful building block for the synthesis of a variety of compounds, including pharmaceuticals, agrochemicals, and materials. It is a versatile boronic acid derivative that can be used as a coupling agent, a reagent in organometallic and other reactions, and as a catalyst in various organic reactions. The presence of the pinacol ester group in 4-NPPBE increases its reactivity, making it an ideal starting material for a variety of synthetic transformations.


The synthesis of 4-NPPBE typically involves the reaction of naphthalene with phenylboronic acid, followed by the reaction of the resulting intermediate with pinacol to yield 4-NPPBE. The reaction conditions for the synthesis of 4-NPPBE can be optimized to obtain the desired yield and purity.


4-NPPBE is an important intermediate in the synthesis of a variety of organic molecules. It can be used as a coupling agent for the synthesis of polymers, as a reagent for the synthesis of organometallic compounds, and as a catalyst for various organic reactions. It is also used as a starting material for the synthesis of a number of pharmaceuticals, agrochemicals, and materials.


4-NPPBE is a highly stable compound and has good shelf life. It is soluble in various organic solvents, such as ethanol, methanol, and DMF. It is also soluble in water, but in limited quantities.


4-NPPBE has a number of applications in organic synthesis, including the synthesis of polymers, organometallic compounds, and various organic molecules. It is also used as a catalyst in various organic reactions. The presence of the pinacol ester group in 4-NPPBE increases its reactivity, making it an ideal starting material for a variety of synthetic transformations.


4-NPPBE is an important intermediate in the synthesis of a variety of organic molecules. It can be used as a coupling agent for the synthesis of polymers, as a reagent for the synthesis of organometallic compounds, and as a catalyst for various organic reactions. It is also used as a starting material for the synthesis of a number of pharmaceuticals, agrochemicals, and materials.


The synthesis of 4-NPPBE typically involves the reaction of naphthalene with phenylboronic acid, followed by the reaction of the resulting intermediate with pinacol to yield 4-NPPBE. The reaction conditions for the synthesis of 4-NPPBE can be optimized to obtain the desired yield and purity.


4-NPPBE is a highly versatile compound and has a wide range of applications in organic synthesis. It is used as a coupling agent for the synthesis of polymers, as a reagent for the synthesis of organometallic compounds, and as a catalyst for various organic reactions. It is also used as a starting material for the synthesis of a number of pharmaceuticals, agrochemicals, and materials. It has a number of advantages, such as easy handling, good solubility, good shelf life, and high storage stability.


Overall, 4-NPPBE is an important boronic acid derivative of naphthalene and phenylboronic acid. It is a versatile building block for the synthesis of a wide range of organic molecules, such as pharmaceuticals, agrochemicals, and materials. It is a highly stable compound and has good shelf life. It is also soluble in various organic solvents, such as ethanol, methanol, and DMF. 4-NPPBE is an important intermediate in the synthesis of a variety of organic molecules and can be used as a coupling agent, a reagent in organometallic and other reactions, and as a catalyst in various organic reactions.


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